
Simcyp LimitedSimcyp provides a modelling and simulation platform which enables pharmaceutical companies to evaluate medicines in the safety of a computer. The particular expertise of Simcyp is modelling the fate of drugs in the body – how they are absorbed, distributed, metabolised, and eliminated (ADME). Simulations are carried out in virtual populations, including children, using data routinely collected during the drug development process. From this, individual patients likely to be at extreme risk from adverse reaction can be identified, and unnecessary exposure to human volunteers and animals can be minimised. The limitations of candidate compounds, including potential drug-drug interactions, can be assessed and managed prior to human studies, allowing better focus of drug development resources. |

